possible/probable CHARGE syndrome: one or two major characteristics and several minor characteristics.definite CHARGE syndrome: 4 major characteristics or 3 major plus 3 minor characteristics.The diagnosis of CHARGE syndrome can be made on clinical grounds 6,11: Clinical presentationĬHARGE syndrome is usually suspected at birth once multiple congenital abnormalities are identified. The incidence is 1-12 per 100,000 births 6.
